Klinefelter's Syndrome Facts

  • Klinefelter's Syndrome occurs in about 1 out of 500 – 1000 males.
  • Small undeveloped testicles are present in all KS men.
  • There is a slight increase in risk of KS in pregnancies after the age of 35.
  • In Australia approximately 60% of males with KS are undiagnosed.
  • KS is the most common cause of male hypogonadism.
  • Treatment for KS is the prescribing of androgen replacement therapy starting at adolescence.
  • Treatment is life-long.

Possible complications include:

  • Attention deficient hyperactivity disorder.
  • Autoimmune disorders such as lupus, rheumatoid arthritis, and Sjogren syndrome.
  • Breast cancer in men.
  • Depression.
  • Learning disabilities, including dyslexia, which affects reading.
  • A rare type of tumor called an extragonadal germ cell tumor.
  • Lung disease.
  • Osteoporosis.
  • Varicose veins.
The most overlooked cause of androgen deficiency
Download the Understanding Klinefelter Syndrome booklet

See your doctor